TUDCA – 300mg Capsules (60 Count)

TUDCA

What is it?

Tauroursodeoxycholic Acid… more commonly known as ‘TUDCA’ for obvious reasons, is found in the bile excreted by our liver and stored in the gallbladder. It is the Taurine conjugate form of Ursodeoxycholic Acid (UDCA). TUDCA is found in very small amounts in human bile but it makes up around 50% of the bile from bears. Infact, TUDCA has been used in Chinese medicine for 100’s of years and before a chemical alternative was found, this ingredient was actually derived from bear bile.

Bile helps with digestion; assisting the body in breaking down fats into fatty acids making them easier for our digestive tract to take in. Bile is made up of 4 main components; Cholesterol, Bilirubin, Bile Acids (also called Bile Salts) and of course, water. When supplemented, TUDCA is in the form of a salt and will be listed on the nutritional panel as “TUDCA (Tauroursodeoxycholic Acid Sodium)”.

What does it do?

We’re going to be completely honest with you here; it is not verified exactly how TUDCA does what it does, but numerous studies have shown very interesting results. TUDCA is actually FDA certified for the treatment of liver diseases such as cholestasis, which is a condition where the production or flow of bile from the liver slows or stops. Supplementing with TUDCA can assist the body in restoring and increasing bile production.

The main benefit TUDCA is known for is improving liver health & function. Studies have cited very impressive results of liver enzymes being reduced after supplementation with TUDCA. Elevated liver enzymes are an indication of poor liver health and function and respectively, low liver enzymes indicate a healthy and functioning liver. Supplementation with TUDCA showed significant reductions in key liver enzymes representing an improvement in liver health.

These improvements in liver health is what makes TUDCA so appealing to users of anabolic substances, especially oral anabolic substances. These substances can take a big toll on our livers health and function which is why ‘On’ and also ‘Off’ cycle support supplements are always recommended to be taken, on top of getting regular blood work to monitor health. TUDCA is regarded as one of the best liver health supplements available today.

The benefits don’t just stop at the liver but to explain the additional benefits of TUDCA we’re going to need to get a little sciency…

Apoptosis is the death of cells which occurs as a normal part of an organism’s growth and development. The main part of the cell that is involved in apoptosis is the mitochondria. Mitochondria are the powerhouses of our cells, responsible for providing energy to the cell. Mitochondria also release and activate certain molecules that play a role in initiating apoptosis. When something unsettles the mitochondrial membrane, a molecule called cytochrome c is released by the mitochondria. Cytochrome c then calls on enzymes called caspases to then initiate a cascade of reactions resulting in apoptosis.

TUDCA is able to protect mitochondria from cellular elements that would normally cause this interference and therefore prevent apoptosis. It does this by preventing a molecule called Bax from being transported to the mitochondria. When Bax is transferred from the cytosol to the mitochondria, it causes the disruption to the mitochondrial membrane initiating this chain of reactions. By TUDCA preventing Bax, it will prevent the unsettling of the membrane which then prevents the release of cytochrome c which then prevents the mitochondria from activating caspases. TUDCA stops cell death by protecting the cell’s mitochondrial membrane.

TUDCA prevents the death of cells by protecting the cells mitochondrial membrane from harmful elements. This process and reaction in the body is why studies are looking at the benefits of TUDCA supplementation for people suffering from neurological diseases such as Parkinson’s Disease, Huntington’s Disease, Alzheimer’s and patients with ALS. These studies and early suggested results are very exciting. TUDCA could have some very beneficial effects for some major diseases.

Studies have also shown improvements in both muscle and liver insulin sensitivity as well as a positive effect on thyroid health. One study using animals and a very large dose of TUDCA showed improvements on neuroprotection from age-related memory loss. These studies were unable to conclusively explain the mechanisms of how TUDCA does this. More studies in humans are required to get more conclusive results and dosages.

WARNING: THIS COMPOUND IS FOR LABORATORY USE ONLY. ALL PRODUCTS ARE STRICTLY FOR RESEARCH PURPOSES ONLY AND ARE NOT FOR HUMAN CONSUMPTION.